Description
Mechanism of Action: SLU-PP-332 activates all three estrogen-related receptors (ERRα, ERRβ, and ERRγ), particularly ERRα, which regulates metabolic pathways usually turned on by exercise. This activation increases mitochondrial function and cellular respiration in energy-intensive tissues like muscle, heart, and brain
“Exercise Mimetic” Effects: In mouse studies, the compound has been shown to induce physiological adaptations similar to aerobic exercise, including improved exercise endurance, increased oxidative muscle fibers, decreased fat mass, and enhanced glucose metabolism.
Potential Therapeutic Use (Preclinical): Research suggests potential applications in treating metabolic diseases such as obesity, type 2 diabetes, non-alcoholic fatty liver disease, heart failure, and age-related muscle loss.
Chemical Nature: Despite being frequently discussed in the “peptide” community, SLU-PP-332 is a small, non-peptide molecule with the chemical formula.
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